The formation and maintenance mechanism of biodiversity has always been an important content of ecological research. In view of the law of community construction, the spatial and temporal pattern of biodiversity is the focus of research. Among them, the most concerned is the species-area theory, but it mainly focuses on the distribution of animals and plants on typical islands, and there are relatively few studies on microorganisms. Since the animal digestive tract is sterile at first, afterwards a specific community is formed by moving in and out and maintaining a certain steady state, so according to the concept of biogeography "islands", the digestive tract can be regarded as the life of microorganisms Special "islands", but the mechanism of the establishment and maintenance of microbial communities in this system is still unclear. Yu Yuhe, a researcher at the Institute of Hydrobiology, Chinese Academy of Sciences, took the model animal zebrafish as the research object and proposed for the first time the semi-closed intestine as an "island" model. The study of the intestinal microbial community in the zebrafish development process (from embryonic development to sexual maturity) revealed the construction and succession laws of the "island" system microorganisms. The results show that the relationship between the microbial species richness of the zebrafish intestine and the intestinal volume and development time conforms to the basic ecological rules of S = cA z and S = cT z. The succession index of zebrafish gut microbial composition and species richness is low, and mainly changes with time, but the succession of its gut microbial community is affected by both niche and random factors. The study also shows that zebrafish is an ideal model for studying the intestinal microbial community construction and related ecological issues in this special "island" system. The research results for this model animal have a mechanism for the formation and maintenance of mammalian and human intestinal microbial communities The research has reference significance. The relevant research results were published in PLoS ONE on January 19, and the main work was completed by Dr. Yan Qingyun. The research was supported by the “973†project of the Ministry of Science and Technology and the National Natural Science Foundation of China. Light Therapy Lamp Guangdong Jishengke Industrial Co.,Ltd , https://www.dgjskpad.com