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Key developments for Thursday, September 24, 2020
The global number of confirmed COVID-19 cases has surpassed 32.3 million, with over 2 million new cases reported since last Thursday. This alarming rate of increase has persisted for weeks, raising concerns about the virus's continued spread. The death toll has exceeded 986,000 worldwide, and the United States remains one of the hardest-hit countries, with nearly 7.2 million cases and over 207,000 deaths. In the past 24 hours alone, more than 800 Americans have lost their lives to the virus, and the country has recorded over 40,000 new infections in just one day. Meanwhile, India continues to lead in daily case growth, reporting over 85,000 new infections each day.
In response to a resurgence of cases, England has reintroduced strict social distancing measures. Prime Minister Boris Johnson announced that office workers should stay home if possible, and weddings will be limited to 15 guests as part of a six-month plan to curb the spread of the virus. These steps highlight the ongoing challenges of managing the pandemic and the need for sustained public health efforts.
Research has shown that the virus affects megakaryocytes in the bone marrow, which can lead to abnormal platelet function and contribute to clotting issues in severe cases. Additionally, the virus appears to attach to the surface of platelets, possibly due to their origin from megakaryocytes. A recent study also found that monocytes, produced by the bone marrow, exhibit impaired function during infection, as the body is forced to produce too many myeloid cells too quickly.
China’s initial lack of transparency in handling the outbreak in Wuhan contributed to the global spread of the virus. A report from the U.S. House Foreign Affairs Committee criticized the World Health Organization for ignoring warnings from Taiwan’s Centers for Disease Control, which could have helped prevent the crisis from escalating into a pandemic.
Before the pandemic, global hunger was already on the rise, but lockdowns, economic downturns, and supply chain disruptions have worsened food insecurity. According to the Council on Foreign Relations, the number of people facing life-threatening food shortages is expected to nearly double, reaching 260 million by the end of 2020. This represents a significant increase from the 135 million people who were at risk in 2019.
Cases are once again rising in Canada, prompting renewed concern about the virus's trajectory. Public health officials are urging caution as new variants emerge and community transmission increases.
Face shields alone are not sufficient to prevent the spread of the virus, as computer simulations show that aerosolized particles can bypass them and be inhaled. To maximize protection, it is recommended to wear a face mask in addition to a face shield.
The FDA has announced stricter requirements for emergency use authorizations of COVID-19 vaccines, including longer follow-up periods—such as 60 days after the second dose—which makes it unlikely that vaccines will be approved before the end of 2020.
A significant portion of the $1 billion allocated under the Cares Act for pandemic response was misused on unrelated projects, raising concerns about accountability and resource allocation. At the same time, there remains a lack of funding for large-scale vaccine distribution, despite the imminent availability of potential vaccines.
New evidence of reinfections has emerged, with genomic data confirming multiple cases where individuals tested positive again after recovering. These findings underscore the importance of continued research and vigilance in understanding the long-term effects of the virus.