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Shanghai Jinma tells you the magical effect of fetal bovine serum
Fetal bovine serum (FBS) is a complex and essential component in cell culture, derived from the blood of healthy eight-month-old fetal calves. Unlike regular serum, which comes from adult animals, FBS is collected through aseptic procedures to ensure purity and consistency. This process involves careful separation and microfiltration, resulting in a high-quality product that is less likely to contain harmful antibodies or complement proteins. Since the fetal calf has not been exposed to external pathogens, FBS is considered one of the safest and most reliable sources for laboratory use.
Shanghai Jinma Experimental Equipment Co., Ltd. specializes in providing a wide range of biological reagents, including high-quality fetal bovine serum from trusted brands such as Gibco, Hyclone, NQBB, and Sigma. Their products are widely used in research, drug development, and biotechnology applications due to their superior quality and consistency.
Fetal bovine serum plays a crucial role in supporting cell growth and maintaining cellular functions. Here are some of its key functions:
1. It provides essential hormones and growth factors that support cell proliferation, especially when the basal medium contains minimal nutrients.
2. FBS contains binding proteins that help transport and regulate vitamins, lipids, and metals, ensuring proper cellular function.
3. Some of these binding proteins can also bind to toxic substances, such as heavy metals and pyrogens, helping to neutralize them and protect the cells.
4. It aids in cell adhesion and spreading on plastic surfaces, which is vital for many in vitro experiments.
5. The serum acts as a buffer to maintain a stable pH environment, which is critical for optimal cell growth.
6. It includes protease inhibitors that prevent damage to cells during processes like trypsinization by inactivating residual enzymes.
In addition to these functions, FBS also contributes to the overall health and viability of cultured cells, making it an indispensable component in modern cell culture practices. Whether you're conducting basic research or developing new therapies, using high-quality FBS ensures more reliable and reproducible results.