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Shanghai Jinma tells you the magical effect of fetal bovine serum
Fetal bovine serum (FBS) is a complex biological fluid derived from the blood of healthy, 8-month-old fetal calves. It is obtained through aseptic collection, centrifugation, and microfiltration processes to ensure purity and quality. Unlike regular serum, FBS has not been exposed to external environments, which means it contains minimal antibodies and complement proteins—making it ideal for cell culture applications where contamination or immune reactions are a concern.
Shanghai Jinma Experimental Equipment Co., Ltd. specializes in providing high-quality biological reagents, including ELISA kits, antibodies, and various types of serum. The company offers reliable sources such as Gibco, Hyclone, NQBB, and Sigma, ensuring that researchers have access to top-grade materials for their experiments.
Fetal bovine serum plays a crucial role in cell culture by:
1. Supplying essential growth factors and hormones that support cell proliferation, especially when the basal medium contains limited nutrients.
2. Providing binding proteins that transport and regulate vitamins, lipids, metals, and other important molecules.
3. Helping neutralize toxic substances like heavy metals and pyrogens through binding mechanisms, thus protecting cells from damage.
4. Facilitating cell adhesion and spreading on plastic surfaces, which is vital for maintaining cell viability and function.
5. Acting as a pH buffer to maintain stable conditions within the culture environment.
6. Delivering protease inhibitors that prevent unwanted enzymatic activity, such as residual trypsin during cell passaging, thereby protecting cells from degradation.
In addition to these functions, FBS also contributes to the overall health and stability of cultured cells, making it an indispensable component in many laboratory settings. Its high quality and consistency make it a preferred choice for researchers working in fields such as biotechnology, pharmaceuticals, and life sciences. Whether you're conducting basic research or developing new therapies, using high-quality FBS can significantly enhance the reliability and reproducibility of your experiments.